KinMet 2008
Satellite Symposium on
Kinetics and Kinetic Modeling of Lipoprotein, Lipid, and Sterol Metabolism in
Systems Ranging from Human Subjects to Cultured Cells
Tuesday, April 15, 2008
12 noon
Omni Hotel,
International Ballroom D (thanks to Julie Green, AHA), Atlanta Georgia.
You are cordially invited to attend our 39th annual meeting. Registration is free and this is among the very few meetings each year at which experimental biomedicine and kinetic modeling are truly integrated. Again this year we are planning three sessions, a format that has worked beautifully for the last several years. To offer a talk for one of the three sessions, simply click on the name of the session chair in the program listing below and send us an e-mail. KinMet is an unofficial satellite symposium of the ATVB and vice versa.
There will be coffee and soft drinks continuously available for attendees at this meeting.
Note to speakers: Time and duration of talks are subject to change. Please check this page just before you depart for Atlanta. Thanks!
| Session 1: 12noon to 2:00 PM | Session 2: 2:00 PM to 4:00PM | Session 3: 4:00 PM to 6:00 PM |
| Modeling
of In Vitro and In Vivo Systems
Chair: Hugh Barrett or Robert Phair |
High
Density Lipoprotein Metabolism and Modeling
Chair: Ernie Schaefer |
ApoB-Containing
Lipoprotein Metabolism and Modeling Chair: Murray Huff |
| 12:00 New approaches to modelling postprandial data – Population kinetics and the possibilities? Hugh Barrett, University of Western Australia | 2:00 Robert I Levy Award Lecture: Lipoprotein kinetics reveals the mechanism of action of lipid modifying drugs: Insights from cultured cells and animal models, Murray Huff, University of Western Ontario | 4:00 ApoB Conversion Rate Constants Only As Good As the Pool Masses, Sekhar Ramakrishnan, Columbia University |
| 12:20 The effect of TRL ApoE content, size and concentration on LDL uptake - A systems biology approach, Brendan O'Malley, Unilever, Bedford, UK | 2:30
Non-CETP Mediated Transfer of HDL cholesteryl ester to LDL in mice,
Marcelo Amar, National Institutes of Health |
4:15 Dose-dependent effect of rosuvastatin on very-low density lipoprotein apolipoprotein C-III kinetics in men with the metabolic syndrome, Esther Ooi, University of Western Australia |
| 4:30 Abnormal lipoproteins kinetics in ESRD HD patients, Katsu Ikewaki, Jikei University School of Medicine | ||
| 12:40 Diurnal rhythm, and other factors, that influence lipogenesis, Elizabeth Parks, University of Texas Southwestern Medical School | 2:45 Genetic Defects and Remodeling of HDL Particles, Ernst Schaefer, Tufts University | 4:45 Inhibition of cholesterol absorption by ezetimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs, Dawn Telford, University of Western Ontario |
| 5:00 Effects of ezetimibe and simvastatin, coadministered and alone, on the in vivo kinetics of apoB-48 in patients with primary hypercholesterolemia Andre Tremblay, Laval University, Quebec City | ||
| 1:10 Measurement of plasma free cholesterol flux: implications on cholesterol homeostasis, Marc Hellerstein, University of California, Berkeley | 3:00 HDL turnover based on the behavior of apoA-I only particles, Larry Rudel, Wake Forest University | 5:15 Modeling of oxylipin transport by lipoproteins,Greg Shearer, Sanford Research/University of South Dakota, Sioux Falls, SD |
| 1:30 The effects of interventions on plasma free cholesterol flux and reverse cholesterol transport in animal models, Jason Voogt, KineMed, Emmeryville, CA | 3:15 The Effects of Niacin on Human Apolipoprotein Metabolism, Margaret Diffenderfer,Tufts University | |
| 1:45 Discussion | 5:30 Discussion - Hot topics for the future | |
| 3:45 Discussion and Break | 6:00 Adjourn | |
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